|Medical Applications for
Micropositioning and Piezo Motor Technology
Read Article in Medical Design Magazine
Piezo Assemblies for Micro Pumps and Valves|
Precison Dosing of Microliter Volumes
Piezo = Miniaturized Technology
Displacement pumps are used worldwide in many diverse branches of industry. Increasing miniaturization means the market for their smaller “relatives“ is also growing: Microdispensers take on distribution and dosing tasks where small volumes in the milliliter, microliter or nanoliter range have to be controlled.
Piezo is the Driving Force
The design is based on the familiar principles of diaphragm pumps and valves and also makes use of the peristaltic principle. The miniaturized drives are based on piezoelectric actuators in various shapes and degrees of integration.
Video: Piezo in Medical Design
Wide Range of Applications for Novel Technology|
In drug discovery and medical engineering, biotechnology or chemical analysis, tiny dispensers accurately dose active substances or medicines. Micropumps take care of the removal of reaction gases in closed processes.
Precision Motion Control for Medical Design
||Adapted for Precision & Force|
The properties of the pump media – viscosity and drop size, for example – determine the different forces which have to be applied and hence the size and type of the piezo actuator used. The piezo displacement is a variable parameter which controls the dosing volume. With micropumps, the frequency also determines the flow rate that can be achieved.
Feature Article in European Medical Device Technology Magazine:
Driving Perfection in Microdosing Applications
|PiezoMove: Moving, Positioning, Scanning|
Piezo linear actuators can be used in micro-valves, particularly where viscous liquids with a tendency towards higher back pressures are processed; where larger strokes of the valve tappet are required, with lever amplification as well.
|Piezo = nano precision = expensive?|
Piezo actuators provide a lot more benefits than “just“ precision. Their excellent dynamics and high force also play a crucial role in many areas, where nanometer precision is not (yet) required: e.g. for fast switching, vibration cancellation, or to adjust tools in machines.
In these applications the piezo actuator is one – if not the only – solution and in the case of the new Piezo
Move OEM actuators, at a very attractive price.
PI supplies a variety of standard integration levels and also customized versions: From simple piezo stack components and preloaded linear actuators through to 6-axis positioning systems with subnanometer precision.
Feature Article in EMDT Magazine:
Piezo Motors and Actuators: Streamlining Medical Device Performance
|Electrophysiology: Piezos Enable Faster Solution Switching|
Siskiyou’s MXPZT-300A fast solution Switcher is based on a fast piezo flexure actuator
|Electrophysiological studies require fast motions of a double- bore (theta-glass) pipette across cell membranes. With a cell held in a patch clamp and monitored electrically, one bore of the pipette flows a buffer solution, while the other carries a drug or other chemical. By quickly sweeping the pipette so one bore or the other suffuses the cell, its electrophysiological response can be correlated to the chemical environment. Piezos are ideal for fast switching, as they offer electromagnetic quietness, good repeatability, high reliability and fast speeds. However, fast acceleration can mean recoil forces excite vibration in the pipette and both piezo and stepper actuators have suffered from these in the past. These cause unwanted, repetitive solution switching for many milliseconds. More....|
|Ultrasonic Piezos Drive Medical Engineering|
|Different Types of Piezo Actuators Solve Different Problems|
|Direct Actuators: Z-Stacks, Shear (X, XY) ||Piezo Flexure Lever Actuators|
|Ultrasonic Linear Motors ||
PiezoWalk® Linear Motors|
All: Sterile, Low Power, No Lubricants, Non- Magnetic, Vacuum Compatible; High Resolution:
|Non-Magnetic Piezo Motors|
OEM PiezoWalk® Linear Motor
PiezoWalk® Linear Actuator
|Dispensers for Bio-Handling|
A single M-664KCEP and a stack of 8 M-664KCEP linear actuators, shown with well plate. The integrated ceramic piezomotor provides high speeds of more than 200 mm/sec.
PI is increasingly employing PILine® piezo ultrasonic drives in its positioning stages as an alternative to motor/lead-
screw designs – particularly when the stages must be small and fast. They achieve positioning accuracies of up to 0.1 µm and speeds of up to several 100 mm/s.
Small and fast is not only a requirement in classical micropositioning technology, however. Piezo ultrasonic motors are also extremely well suited to applications where the accuracy requirements are not quite so demanding – in the range between 5 and 100 micrometers for example, which is usually sufficient for industrial automation and handling tasks.
PI has developed the low cost M-664KCEP dispenser drive with PILine® piezo ultrasonic motors for this kind of application. Eight or more of these drives stacked together can move pipettes vertically and independently of each other in order to dispense liquids into well plates. A single actuator is only 9 millimeters wide to match the standardized sample holder.
The M-664KCEP covers the travel range of 50 millimeters in less than 250 milliseconds and generates forces of up to 4 N. The resolution of the positioning sensor is matched to the application and amounts to 5 micrometers.
|Six Axis Motion a Small Package |
Miniature 6-Degree of Freedom Hexapod Robotics Positioner
Read more about Medical Robots (6-Axis Hexapods)
|PI's M-810 miniature 6-Axis positioner combines all advantages of PI’s other proven parallel-kinematic hexapod robot systems in the smallest of packages. With a diameter of only 10 cm and a height of less than 12 cm, the M-810 offers travel
ranges of up to 40 mm in the XY plane and 13 mm in the Z direction. Despite of its small size, the hexapod can reliably position loads of up to 5 kg at velocities of 10 mm/s.
The small envelope was made possible by the usage of new technologies for encoders, motors and reference switches. Nevertheless, the Mini-Hexapod is 100% compatible with PI's tried and proven Hexapods 6-Axis controllers and software.
As with other parallel-kinematics positioners from PI, the six high resolution actuators are connected directly to a single moving platform. The user is able to define the center of rotation (pivot point) independent of platform motion with a simple software command.
In contrast to conventional, stacked, multi-axis systems, there is no accumulation of guiding and lever-arm errors
|Piezo Stages for Bio-Medical Imaging and Microscopy|
|Piezo & Precision Actuator Systems in Other Bio-Medical Applications:|
|Inner Ear Research: Piezo chip actuator in research for Stimulation of hair cells in the inner ear|
Biomedial Imaging: |
Characterizing point spread functions of two-photon fluorescence microscopy in turbid medium
|Electrophysiology: Piezo Technology Enables Faster Solution Switching|
|Piezoelectric Effect and Growth Control in Bone|
P-239 Piezo Actuator Medical Application: Development of a Mechanical Testing |
and Loading System for Trabecular Bone Studies
M-126 Precision Linear Stage and M-231 Linear Actuator Application in Medical Robotics and |
Computer Assisted Surgery MEM Surgery: an integrated test-bed for vascular surgery
Hexapod Bio-Medical Application: A technical review on the |
orthopedic compliant robotic arms
PI Hexapod Application in Medical Engineering Adaptation of a hexapod-based robotic system for extended |
endoscope-assisted transsphenoidal skull base surgery
M-850 Hexapod Neuro Surgery Application: A robotic neuro-surgery system and its |
calibration by using a motion tracking system
M-230 Precision Actuator Application in Medical Engineering Time kinetics of bone defect|
healing in response to BMP-2 and GDF-5 characterised by in vivo biomechanics
|M-850 Hexapod Bio-Medical Application: A Stewart platform for precision surgery|
-850 Hexapod Dental Engineering Application: Aufbau und Erprobung eines neuartigen Meßsystems|
für die dentale Biomechanik
M-850 Hexapod Application in Medical Engineering: Eine konfokale Messsonde zur hochpräzisen |
|Custom M-850 Hexapod as Medical Robot for Spine Surgery|
M-840 Hexapod Bio-Medical Application: Subcellular Motion Compensation for |
Minimally Invasive Microscopy, In Vivo. Evidence for Oxygen Gradients in Resting Muscle
|Custom M-850 Hexapod as Medical Robot for Spine Surgery|
M-824 High Precision Hexapod Bio-Medical Application in Prospective head movement correction for high |
resolution MRI using an inbore optical tracking system